Innovative Support for Major Depressive Disorder
Comprehensive IV Therapy to Enhance Mood, Balance Neurotransmitters, and Promote Relaxation
Major Depressive Disorder (MDD) Protocol
Here’s a comprehensive IV nutrient and hydration therapy designed for individuals with Major Depressive Disorder (MDD). This protocol focuses on nutrients and compounds that support mood regulation, neurotransmitter balance, and nervous system function. It includes a breakdown of each component’s benets, safety considerations, suggested dosages, and recommended administration frequency.
Vitamin B-Complex
Benefits: Essential for brain function and neurotransmitter production, supports energy metabolism and mental clarity. Addresses deficiencies linked to depressive symptoms.
Safety: Generally safe; use caution with genetic polymorphisms (e.g., MTHFR).
Dosage: B1: 50–100 mg, B2: 10–20 mg, B3: 50–100 mg, B5: 50–100 mg, B6: 50–100 mg, B12: 500–1000 mcg.
Frequency: 1–2 times per week based on individual needs.
Magnesium Sulfate
Benefits: Vital for neurotransmitter balance, muscle relaxation, and nervous system regulation. Helps with depressive symptoms, mood, and sleep.
Safety: High doses may cause diarrhea or low blood pressure. Monitor for clients with renal impairment.
Dosage: 1–2 grams.
Frequency: 1–2 times per week based on tolerance and deficiency.
Vitamin C (Ascorbic Acid)
Benefits: Reduces oxidative stress, supports dopamine synthesis, and enhances neurotransmitter health. Alleviates depressive symptoms.
Safety: Well-tolerated; high doses may cause gastrointestinal discomfort.
Dosage: 5–10 grams.
Frequency: 1–2 times per week.
L-Tryptophan or 5-HTP
Benefits: Supports serotonin production to improve depressive symptoms. L-Tryptophan is a serotonin precursor, while 5-HTP acts more directly.
Safety: Avoid for clients on SSRIs or MAOIs due to serotonin syndrome risk.
Dosage: L-Tryptophan: 500–1000 mg; 5-HTP: 100–200 mg.
Frequency: 1 time per week.
N-Acetyl Cysteine (NAC)
Benefits: Boosts glutathione production, reducing oxidative stress. Supports mood regulation and treatment-resistant depression.
Safety: High doses may cause gastrointestinal side effects. Use caution with asthma patients.
Dosage: 500–1000 mg.
Frequency: 1 time per week.
L-Taurine
Benefits: Regulates the nervous system, supports GABA production, and reduces depressive and anxious symptoms.
Safety: Safe at low doses; high doses may interact with blood pressure medications.
Dosage: 500–1000 mg.
Frequency: 1 time per week.
Glutathione (Antioxidant)
Benefits: Reduces inflammation and oxidative stress, supporting mood, brain health, and overall wellness.
Safety: Safe when administered slowly; high doses may cause flushing or stomach upset.
Dosage: 600–1200 mg.
Frequency: 1 time per week.
Normal Saline or Lactated Ringer’s Solution
Benefits: Hydration supports cognitive function, mood, and cellular health. Reduces fatigue related to dehydration.
Safety: Use with caution for individuals with heart or kidney conditions.
Dosage: 500–1000 mL.
Frequency: Included in each IV session.
