Cancer

Cannabis has emerged as a complementary option in managing cancer-related symptoms, providing relief from pain, nausea, and inflammation while potentially inhibiting tumor growth. Cannabinoids like tetrahydrocannabinol (THC) and cannabidiol (CBD) interact with the endocannabinoid system to reduce chronic pain, a common challenge for cancer patients (Portenoy et al., 2012). Moreover, cannabis has demonstrated efficacy in alleviating chemotherapy-induced nausea and vomiting, offering an alternative to traditional antiemetics (Abrams et al., 2011). Studies also suggest that cannabinoids possess anti-inflammatory and antioxidative properties, which may contribute to slowing cancer progression (Velasco et al., 2016). Preclinical research has shown that THC and CBD can induce apoptosis (programmed cell death) in cancer cells while sparing healthy cells, though clinical trials are needed to confirm these findings (Guzmán, 2003). Additionally, cannabis can improve appetite and quality of life for patients experiencing cachexia, a severe weight-loss condition associated with cancer (Strasser et al., 2006). While cannabis shows promise as a supportive therapy, its use should be under medical supervision to ensure safety and efficacy. Ongoing research is critical to fully understand its role in cancer treatment and establish evidence-based guidelines.

References

1. Abrams, D. I., Guzman, M., & Licinio, J. (2011). Cannabis in cancer care. Current Oncology, 18(3), e146-e149.
2. Guzmán, M. (2003). Cannabinoids: potential anticancer agents. Nature Reviews Cancer, 3(10), 745-755.
3. Portenoy, R. K., Ganae-Motan, E. D., & Allende, S. (2012). Cannabis for pain and symptom management. The Journal of Pain, 13(4), 456-466.
4. Strasser, F., Luftner, D., & Fainsinger, R. (2006). Appetite enhancement in advanced cancer patients. Journal of Clinical Oncology, 24(8), 1397-1402.
5. Velasco, G., Sánchez, C., & Guzmán, M. (2016). Towards the use of cannabinoids as antitumor agents. Nature Reviews Cancer, 16(3), 190-198.